Table 9 Relative RYR 1 allele ratios of LCLs after incubation with actinomycin D
Normalized ratios LCL #5 | Actinomycin D incubation time (h) mean ± stdev. | |||
|---|---|---|---|---|
| Â | 0 | 2 | 7 | 24 |
Wild type RYR1 (CV%) | 1.22 ± 0.25 (20.70%) | 1.44 ± 0.24 (16.83%) | 1.43 ± 0.22 (15.17%) | 1.12 ± 0.07 (6.24%) |
Mutant RYR1 | 1.00 | 1.00 | 1.00 | 1.00 |
Normalized ratios LCL #6 | Â | Â | Â | Â |
Wild type RYR1 (CV%) | 1.86 ± 0.28 (15.21%) | 1.82 ± 0.15 (8.14%) | 1.86 ± 0.43 (23.38%) | 1.67 ± 0.17 (10.05%) |
Mutant RYR1 | 1.00 | 1.00 | 1.00 | 1.00 |