Figure 1From: The role of SH3BP2 in the pathophysiology of cherubismGene map and protein structure of human SH3BP2 indicating mutations in the canonical cherubism mutation interval (amino acids 415-420) and mutations reported in the pleckstrin homology (PH) domain. The mutation in the SH2 domain has been found in tumor tissue of a patient with giant cell tumor. (Modified after Ueki et al., 2001)Back to article page