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Table 8 Associations between ARM and maternal use of drugs against nausea and vomiting

From: Maternal drug use and the risk of anorectal malformations: systematic review and meta-analysis

 

Maternal use of drugs against nausea and vomiting

 

Ref.

First author, year

Exposure

ORcrude [95% CI]

ORadj [95% CI]

Adjustment/matching factors

[49]

Pasternak, 2013

Metoclopramide

0.7 [0.34, 1.54]c

0.8 [0.36, 1.66]b

Matched and adjusted for hospitalization for hyperemesis gravidarum or nausea and vomiting, and use of other antiemetics in the first trimester

[78]

Källén and Mottet, 2003

Meclozine

2.3 [0.99, 4.50]a

–

–

  1. aRisk Ratio (RR)
  2. bPrevalence odds ratio (POR)
  3. cNeuroleptics other than dixyrazine or prochloperazine