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Table 3 List of IDeAl added aspects, explanation in brackets

From: Lessons learned from IDeAl — 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials

adaptive combination

adaptive graph-based multiple

adaptive LASSO

adaptive strategy

adjusted significance level

assessment of randomisation procedures

Bayesian decision theory

biased corrected test (likelihood ratio test)

biasing policy

BIC criterion

blocked ANOVA

bootstrap (constrained parametric bootstrap procedure)

causal inference

CorrMixed

decision theoretic aspect (Bayesian decision theoretic)

dOFV (delta objective function values)

dose-response

EffectTreat

ERDO (evaluation of randomisation procedures for design optimisation)

similarity of dose response

FDR (false discovery rate)

first-in-human

Fisher information matrix

SLOPE (group SLOPE, geneSLOPE)

k-means

linked assessment criterion

many-to-one

maximum likelihood estimation

MC-AGQ

MC-HMC

MCPMod (closed MCPMod)

confidence bands for difference of curves

meta-analysis

meta-analytic paradigma

mixed effects model

MIXFIM

model averaging

model selection

monte-carlo

stochastic simulation

non-parametric

open-label

optimal-design (compound D-optimality criterion)

parametric power estimation

permutation test

PESEL (penalized semi-integrated likelihood method)

pharmacometrics

prior information

randomisation based inference

randomizeR

real world data

Robustness

SIR (sampling importance resampling)

scepticism factor (scepticism)

selection bias

sequential analysis

Simulation

SPF (surrogate predictive function)

stratification

personalised medicine

SURROGATE

TestingSimilarity

threshold-crossing

time trend bias

two-stage adaptive design

type-I-error probability

intersection-union principle