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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Research, diagnosis and education in inborn errors of metabolism in Colombia: 20 years’ experience from a reference center

Fig. 3

Use of bioinformatics tools for the study of IEM. Tertiary structure of human IDS (a) and GALNS (b) enzymes were modeled by protein threading based on the reported structure of other lysosomal enzymes. IDS and GALNS 3D models have been used in phenotype-genotype correlation studies as well as for the design of epitope-specific antibodies. N-glycosylations were modeled by using GlyProt at GLYCOSCIENCES.de server. c Gene enrichment analysis for impaired cellular process in MPS models, identified by a computational systems biology approach

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172