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Table 2 Baseline demographics and comorbidities

From: The patient journey toward a diagnosis of hereditary transthyretin (ATTRv) amyloidosis

 

Newly diagnosed ATTRv Amyloidosis patients N = 141

Matched controlsa N = 423

p value

Age, year, mean (SD)

62.5 (14.3)

62.5 (14.2)

n/ad

 18–34, n (%)

6 (4.3)

18 (4.3)

 

 35–54

27 (19.1)

81 (19.1)

 

 55–64

52 (36.9)

156 (36.9)

 

 65+

56 (39.7)

168 (39.7)

 

Female, n (%)

76 (53.9)

228 (53.9)

n/ad

Region, n (%)

 Midwest

26 (18.4)

78 (18.4)

n/ad

 Northeast

47 (33.3)

141 (33.3)

 

 South

55 (39.0)

165 (39.0)

 

 West

13 (9.2)

39 (9.2)

 

Insurance type, n (%)b

  

0.087

 PPO/POS

99 (70.2)

239 (56.5)

 

 HMO/EPO

8 (5.7)

30 (7.1)

 

 CDHP/HDHP

14 (9.9)

72 (17.0)

 

 Comprehensive

20 (14.2)

80 (18.9)

 

Charlson comorbidity index, mean (SD)

2.7 (3.0)

1.1 (1.9)

< 0.001

Number of chronic conditions, mean (SD)

5.1 (2.7)

3.2 (2.3)

< 0.001

Health care provider, n (%)

  

0.018

 Primary care

65 (46.1)

230 (54.4)

 

 Cardiologist

5 (3.5)

10 (2.4)

 

 Dermatologist

4 (2.8)

16 (3.8)

 

 Gastroenterologist

6 (4.3)

6 (1.4)

 

 Neurologist

6 (4.3)

2 (0.5)

 

 Rheumatologist

5 (3.5)

6 (1.4)

 

 Otherc/unknown

50 (35.5)

153 (36.2)

 
  1. ATTRv hereditary transthyretin, CDHP/HDHP consumer directed health plan/high deductible health plan, EPO exclusive provider organization, HMO health maintenance organization, PPO/POS preferred provider organizations/point of service
  2. aMatched with age, gender, and region
  3. bTwo matched controls had missing/unknown insurance type
  4. cIncludes podiatrists and individual specialties with count < 5
  5. dMatched exactly