Table 2 immunological features of LICS patients
Family 1 | Family 2 | ||||
|---|---|---|---|---|---|
A | B | C | D | E* | |
Immunological features | |||||
IgA (g/L)a | 2.2 (0.16–1.1) | 0.6(0.16–1.1) | 1.1(0.16–1.1) | 1.0(0.16–1.1) | 0.7 (0.19–2.2) |
IgG (g/L)a | 11.1 (2.6–15.2) | 7.5 (2.6–15.2) | 11.6 (2.6–15.2) | 5.3 (2.6–15.2) | 8.2 (2.6–15.2) |
IgM (g/L)a | 0.6 (0.1–1.2) | 0.6 (0.1–1.2) | 2.3 (0.1–1.2) | 1.2 (0.1–1.2) | 0.7 (0.1–1.2) |
IgE (g/L) | 344 | 228 | 34 | 273 | 314 |
T cells | |||||
CD4 + (109/L)b | NA | 2.42 (1.7–4.1) | 1.12 (1.3–4.1) | 28%c | 1.38 (0.7–2.0) |
CD8 + (109/L)b | NA | 1.06 (0.7–1.8) | 0.41 (0.5–1.6) | 14%c | 0.38 (0.5–1.4) |
T cell proliferation to | |||||
Mitogensd | NA | = | = | NA | ↓/= |
Antigense | NA | = | NA | NA | = |
B cells (109/L)b | NA | 1.36 (0.8–2.2) | 0.68 | 50%c | 0.98 * |
Antibody titers to | |||||
Diphtheria | NA | = | NA | NA | ** |
Pneumococcal vaccination | NA | = | NA | NA | ** |
Delayed type hypersensitivity testing | |||||
Tetanus | NA | = | NA | NA | ** |
Candida | NA | = | NA | NA | ** |