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Table 4 Clinical, laboratory, imaging and related pathologic findings in DSVPTC

From: Sonographic characteristics of diffuse sclerosing variant of papillary thyroid carcinoma with histopathological correlation: a preliminary study

Case

Age

Sex

Preoperative thyroid function

Operation way

Background

Nodule

Metastatic lymph node

“Snowstorm” pattern on sonogram

Pathology

Ultrasound

Pathology

Ultrasound

Pathology

1

16

F

Normal

Total thyroidectomy + LND

Bilateral lobes

Diffused distribution of tumor cells and psammoma bodies in bilateral lobes

-

-

+

+

2

38

F

TSH above the normal range

Total thyroidectomy + LND

Left lobe

Diffused distribution of tumor cells and psammoma bodies in the left lobe and scattered distribution in the right lobe

-

-

+

+

3

19

F

Normal

Total thyroidectomy + LND

Left lobe

Diffused distribution of tumor cells and psammoma bodies in the left lobe

One nodule in the right lobe

One localized cPTC lesion in the right lobe

+

+

4

35

F

TgAb positive

Right thyroidectomy + LND

Right lobe (a few microcalcifications in the left lobe)

Diffused distribution of tumor cells and psammoma bodies in the right lobe

-

-

+

+

5

35

F

TPOAb positive

Total thyroidectomy + LND

Right lobe

Scattered distribution of tumor cells and psammoma bodies with lymph vessel tumor emboli in the right lobe

Multiple nodules in the right lobe

Gathering areas of tumor cells and psammoma bodies

+

+

6

36

F

TSH above the normal range, TgAb and TPOAb positive

Total thyroidectomy + LND

Right lobe

Diffused distribution of tumor cells and psammoma bodies in the right lobe

One nodule in the right lobe

A fibrotic nodule

+

+

7

35

F

TSH above the normal range, TgAb and TPOAb positive

Total thyroidectomy + LND

No

Scattered distribution of tumor cells and psammoma bodies in bilateral lobes, decreasing with distance from the nodule in the right lobe with lymph vessel tumor emboli

One nodule in the right lobe

Gathering area of tumor cells and psammoma bodies

+

+

8

67

F

TgAb positive

Total thyroidectomy + LND

No

Scattered distribution of tumor cells and psammoma bodies in the right lobe and sporadic tumor cells in the left lobe

Multiple nodules in the right lobe

Gathering areas of tumor cells and psammoma bodies in the right lobe

+

+

9

26

F

Normal

Left thyroidectomy + LND

No

Scattered distribution of tumor cells and psammoma bodies in the left lobe, decreasing with distance from the nodule with lymph vessel tumor emboli

One nodule in the left lobe

Gathering area of tumor cells and psammoma bodies in the left lobe

-

+

10

53

M

Normal

Total thyroidectomy + LND

No

Scattered distribution of tumor cells and psammoma bodies in the left lobe

One nodule in the left lobe

A fibrotic nodule in the left lobe

+

+

F: female; M: male; LND: lateral neck dissection