Fig. 3From: Abnormal activation of MAPKs pathways and inhibition of autophagy in a group of patients with Zellweger spectrum disorders and X-linked adrenoleukodystrophyLC3. Autophagy is downregulated in PBMC of ZSDs and X-ALD patients. Representative immunoblots for LC3-I and LC3-II in control (CTL) and in X-ALD and ZSDs patients. Protein levels are normalized respect to GAPDH. The histograms below show the LC3-II/LC3-I ratio levels relative to CTLBack to article page