Table 2 Glucolipid metabolic indices of PHP1, normal control and PHPT
PHP1 (n = 49) | Normal control (n = 30) | PHPT (n = 64) | p1 | p2 | p3 | |
|---|---|---|---|---|---|---|
FBG (mmol/L) | 4.80 ± 0.39 | 4.90 (4.30–6.00) | 5.40 (3.80–14.30) | 1.000 | < 0.001 | < 0.001 |
Ins (μIU/mL) | 6.00 (1.90–17.50) | 5.57 ± 2.85 | 7.80 (2.90–19.50) | 1.000 | 0.005 | 0.031 |
HOMA-IR | 1.24 (0.38–4.04) | 1.24 ± 0.66 | 1.77 (0.71–8.01) | 1.000 | 0.001 | 0.001 |
HOMA-IS | 0.81 (0.25–2.63) | 0.92 (0.35–3.91) | 0.57 (0.12–1.41) | 1.000 | 0.001 | 0.001 |
HOMA-β (%) | 97.08 (26.25–312.50) | 80.48 ± 41.53 | 72.40 (23.33–313.33) | 0.060 | 0.961 | 0.028 |
TC (mmol/L) | 4.37 ± 0.79 | 4.18 ± 0.71 | 4.88 ± 1.05 | 1.000 | 0.006 | 0.012 |
TG (mmol/L) | 0.95 (0.33–2.63) | 0.99 (0.31–2.95) | 1.17 (0.31–4.22) | 0.509 | 0.126 | 0.022 |
Hypertriglyceridemia [n, (%)] | 8 (16.3%) | 3 (10%) | 13 (20.3%) | 0.523 | 0.255 | 0.631 |
HDL-C (mmol/L) | 1.26 (0.77–2.19) | 1.26 (0.85–2.27) | 1.32 ± 0.31 | 0.777 | 0.930 | 0.946 |
Hypo-HD-lipoproteinemia [n, (%)] | 3 (6.1%) | 1 (3.3%) | 5 (7.8%) | 0.146 | 0.707 | 0.228 |
LDL-C (mmol/L) | 2.61 ± 0.62 | 2.62 ± 0.58 | 2.86 ± 0.94 | 0.616 | 0.150 | 0.045 |
Hyper-LD-lipoproteinemia [n, (%)] | 5 (10.2%) | 3 (10%) | 16 (25%) | 0.509 | 0.309 | 0.052 |
Leptin (ng/ml) | 2.43 (0.10–6.39) | 1.16 (0.09–9.02) | 2.24 (0.10–8.24) | 1.000 | 0.037 | 0.124 |
Adiponectin (μg/ml) | 4.64 (2.27–81.80) | 5.39 ± 3.05 | 4.95 (1.80–12.24) | 0.889 | 0.964 | 0.977 |
FGF21 (pg/ml) | 167.46 (17.82–975.23) | 165.29 (63.19–649.68) | 255.74 (45.59–847.88) | 1.000 | 0.094 | 0.019 |
TNFα (pg/ml) | 10.74 ± 4.13 | 15.47 ± 6.65 | 11.48 (3.82–44.61) | 0.002 | 0.041 | 0.481 |
LAR | 0.19 (0.01–3.19) | 0.34 (0.02–2.26) | 0.50 (0.01–2.24) | 0.604 | 0.062 | 0.141 |