Table 3 Demographic and glucolipid metabolic indices of PHP1 patients of different molecular subgroups

M/F (n/n)

26/23

8/6

17/18

14/16

Age (years)

25.1 ± 10.8

25.1 ± 8.0

27.4 ± 10.2

25.1 ± 10.8

 < 18 yo [n, (%)]

11 (22.4%)

5 (35.7%)

6 (17.1%)

9 (30%)

 ≥ 18 yo [n, (%)]

38 (77.5%)

9 (64.3%)

29 (82.9%)

21 (70%)

BMI (kg/m²)

23.88 ± 5.23

25.14 ± 5.72

23.20 ± 4.63

21.72 ± 3.07

Overweight [n, (%)]

11 (22.4%)

3 (21.4%)

8 (22.9%)

6 (20%)

Obese [n, (%)]

7 (14.3%)

3 (21.4%)

4 (11.4%)

0 (0%)

Overweight/obese [n, (%)]

18 (36.7%)

6 (42.8%)

12 (34.3%)

6 (20%)

FBG (mmol/l)

4.80 ± 0.39

4.61 ± 0.32

4.84 ± 0.38

4.90 (4.30–6.00)

Ins (μIU/ml)

6.00 (1.90–17.50)

5.40 (1.90–13.80)

6.70 (2.10–17.50)

5.57 ± 2.85

TG (mmol/L)

0.95 (0.33–2.63)

1.16 ± 0.74

1.04 ± 0.48

0.99 (0.31–2.95)

LDL-C (mmol/L)

2.61 ± 0.62

2.25 (1.45–4.04)

2.64 ± 0.55

2.62 ± 0.58

HOMA-IR

1.24 (0.38–4.04)

1.34 ± 0.79

1.35 (0.48–4.04)

1.24 ± 0.66

HOMA-IS

0.81 (0.25–2.63)

0.83 (0.37–2.63)

0.75 (0.25–2.10)

0.92 (0.35–3.91)

HOMA-β (%)

97.08 (26.25–312.50)

108.00 (38.00–306.67)

94.79 (26.25–312.50)

80.48 ± 41.53

Leptin (ng/ml)

2.43 (0.10–6.39)

1.57 (0.12–6.17)

2.48 (0.10–6.39)

1.16 (0.09–9.02)

Adiponectin (μg/ml)

4.64 (2.27–81.80)

5.22 ± 2.19

4.57 (2.58–81.80)

5.39 ± 3.05

FGF21 (pg/ml)

167.46 (17.82–975.23)

163.69 (59.31–975.05)

154.45 (17.82–693.97)

165.29 (63.19–649.68)

TNFα (pg/ml)

10.74 ± 4.13

10.51 ± 4.05

10.82 ± 4.29

15.47 ± 6.65

LAR

0.34 (0.02–2.26)

0.65 ± 0.78

0.38 (0.02–1.81)

0.19 (0.01–3.19)