Fig. 1From: Real-life impacts of olipudase alfa: The experience of patients and families taking an enzyme replacement therapy for acid sphingomyelinase deficiencySurvey reported frequency of ASMD symptoms before (n = 10) and after (n = 10) treatment with olipudase alfa. Symptom categories are tiredness and fatigue (a), abdominal pain (b), organ enlargement (c), vomiting and nausea (d), bone pain (e), bruising (f), chronic headaches (g), infections over a 6-month period (h), and shortness of breath (i)Back to article page