Fig. 4

Perceived disease severity before and after the idursulfase-IT trial based on caregivers’ feedback. Only the total column reflects all interviews; age at study entry was not available for children outside the USA and Canada. ^a One participant whose child was in the age 2–6 years category was unable to provide a response to this question; one participant whose child’s age at study entry was unavailable was unable to provide a response to this question. ^b Two participants whose children were in the age 2–6 years category were unable to provide responses to this question; one participant whose child’s age at study entry was unavailable was unable to provide a response to this question. ^c Three participants, two of whom had children in the age 2–6 years category and one of whom had a child in the substudy, were unable to provide a response to this question; one participant whose child’s age at study entry was unavailable was unable to provide a response to this question. IT Intrathecal