Table 2 Clinical data for four patients with lymphangioleiomyomatosis who experienced postoperative pneumothorax
From: Intraoperative mechanical ventilation and incidence of pneumothorax in lymphangioleiomyomatosis
Characteristics | Case 1 | Case 2 | Case 3 | Case 4 |
|---|---|---|---|---|
Age (y) | 34 | 49 | 30 | 33 |
Diagnosis | Sporadic-LAM | TSC-LAM | Sporadic-LAM | Sporadic-LAM |
Preoperative variables | Â | Â | Â | Â |
CT grade | / | II | III | III |
VEGF-D (pg/mL) | / | 679 | 1734 | 1211 |
FEV1/Pred (%) | / | / | 64 | 75 |
DLco/Pred (%) | / | / | 25 | 47 |
6MWD (m) | / | 590 | 410 | 472 |
PaO2 (mmHg) | 73 | 65.5 | 62 | 85 |
SpO2 (%) | 87 | 100 | 90 | 95 |
Number of preoperative PTX episodes | 7 | 2 | 1 | 0 |
History of pleurodesis | No | No | No | No |
Menstruation status | Pre-menopausal | Peri-menopausal | Pre-menopausal | Pre-menopausal |
Current pregnancy | No | No | Yes | Yes |
Preoperative mTOR inhibitors therapy | No | No | No | No |
Intraoperative variables | Â | Â | Â | Â |
Surgical type | VATS lobectomy | VATS pleurodesis | Cesarean section | Cesarean section |
Surgery duration (min) | 118 | 75 | 60 | 63 |
ASA physical status | 3 | 2 | 3 | 4 |
Anesthetic technology | GA | GA | CSEA | GA |
Anesthesia duration (min) | 153 | 125 | 115 | 95 |
Mechanical ventilation | Yes | Yes | No | Yes |
 Ventilation duration (min) | 153 | 112 | / | 9360 |
 Mean peak airway pressure (mmHg) | 19 | 17 | / | 29 |
 Respiratory rate | 22 | 11 | / | 18 |
 Extubation | Yes | Yes | / | No |
Back to ICU | Yes | No | Yes | Yes |
Date of postoperative PTX | POD 10 | POD 20 | POD 13 | POD 8 |