Table 1 Inflammation symptoms and malignant symptoms
Symptoms | Involved organs and manifestations |
|---|---|
Inflammatory symptoms | • Rash • Ear canal lesions: otorrhea or suspected hearing impairment • Bone damage: pain, limited mobility, hollow mass of the calvarium, eosinophilic granuloma of the long bones,scoliosis or vertebral compression fracture • Gastrointestinal symptoms: diarrhea, failure to thrive or evidence of malabsorption • Pulmonary symptoms: cough, shortness of breath • Liver symptoms: jaundice, low whiteness proteinemia, etc • Endocrine system symptoms: short stature, growth failure precocious or delayed puberty,hypothyroidism • Central nervous system symptoms: diabetes insipidus, neurodegenerative changes |
Malignant symptoms | • Noninfectious persistent fever • Infiltrated symptoms: gingival or palatal swelling, splenomegaly, mass of body or organ, lymphadenopathy • Hematologic symptoms: leukopenia, thrombocytopenia, anemia not explained by other causes |